Alnylam
Commercial-stage biopharmaceutical company that develops RNA-interference therapeutics for rare, cardiometabolic, hepatic, and central nervous system diseases.
Therapeutic areas
Selected products and programs
Linked curated drug profiles
Selected active clinical trials
Phase 3 · Recruiting · Hereditary Transthyretin-Mediated Amyloidosis With Polyneuropathy
TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With CardiomyopathyPhase 3 · Recruiting · Transthyretin Amyloidosis With Cardiomyopathy
Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular DiseasePhase 3 · Recruiting · High Risk Cardiovascular Disease
A Study to Evaluate ALN-4285 in Adult Healthy VolunteersPhase 1 · Recruiting · Healthy Volunteers
A Study to Evaluate ALN-2232 in Participants With ObesityPhase 1 · Recruiting · Obesity
A Study to Evaluate ALN-4324 on Insulin Sensitivity in Adults With Type 2 Diabetes MellitusPhase 2 · Recruiting · Type 2 Diabetes Mellitus (T2DM)
Selected patent records
patisiran sodium · Expires 2027-10-03
US 10131907givosiran sodium · Expires 2028-08-24
US 8828956givosiran sodium · Expires 2028-12-04
US 10806791vutrisiran sodium · Expires 2028-12-04
US 9370581vutrisiran sodium · Expires 2028-12-04
US 11141378patisiran sodium · Expires 2029-04-15
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