PHARMA SIGNALOPEN RESEARCH PLATFORM →
COMPANY RESEARCH PROFILE · UPDATED 2026-09-29

Ionis Pharmaceuticals

Pioneer in antisense oligonucleotide therapeutics with partnered and wholly owned programs.

TICKERIONS
HEADQUARTERSCalifornia, USA
STAGEApproved
ACTIVE TRIALS20

Therapeutic areas

Neurologycardiometabolicrare diseases

Selected products and programs

Spinraza (royalties)Tegsedi

Linked curated drug profiles

No curated drug entity is linked in the current pilot.

Selected active clinical trials

REVEAL: A Phase 3 Study of Obudanersen (ION582) in Angelman Syndrome

Phase 3 · Recruiting · Angelman Syndrome

Donidalorsen Treatment in Children With Hereditary Angioedema

Phase 3 · Recruiting · Hereditary Angioedema (HAE)

A Study of Olezarsen for the Treatment of Familial Chylomicronemia Syndrome (FCS) in Pediatric Participants

Phase 3 · Recruiting · Familial Chylomicronemia Syndrome

Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ION464 Administered to Adults With Multiple System Atrophy (HORIZON)

Phase 1 · Recruiting · Multiple System Atrophy

A Study to Assess the Safety, Tolerability and Efficacy of ION775

Phase 2 · Recruiting · Hypertriglyceridemia

ATTUNE: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Intrathecally-Administered ION440 in Participants With Methyl CpG Binding Protein 2 (MECP2) Duplication Syndrome (MDS)

Phase 1 · Recruiting · Methyl CpG Binding Protein 2 (MECP2) Duplication Syndrome

Selected patent records

US 8697860

inotersen sodium · Expires 2031-04-29

US 9061044

inotersen sodium · Expires 2031-04-29

US 9399774

inotersen sodium · Expires 2031-04-29

Primary and company sources

Company and pipeline information can change. Verify material decisions against the linked primary sources.

Evidence & limits

Source: Open the source record

Record identifier
/companies/ionis-pharmaceuticals/
Event / action date
Not separately retained
Source update date
Not separately retained
Platform retrieval / processing date
Not separately retained

What it supports. Connections found through the catalog, identifiers, or name and alias matching, with source links where retained.

Limits. A company association is not proof of ownership or sponsorship of every linked record. Product, substance, parent-company, and subsidiary relationships may differ.

Connection basis. Catalog, identifier, or normalized name association. Product and company connections are research leads, not ownership determinations.

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