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COMPANY RESEARCH PROFILE · UPDATED 2026-09-29

Ono Pharmaceutical

Research-driven pharmaceutical company with a substantial oncology portfolio and pipeline, including the anti-PD-1 antibody Opdivo and multiple combination programs.

TICKER4528.T
HEADQUARTERSOsaka, Japan
STAGEApproved
ACTIVE TRIALS37

Therapeutic areas

OncologyImmunologyNeurology

Selected products and programs

OpdivoQinlock

Linked curated drug profiles

nivolumab

PD-1-directed monoclonal antibody

Selected active clinical trials

ONO-2017 Study Japanese Patients With Primary Generalized Tonic Clonic Seizures.

Phase 3 · Recruiting · Epilepsy, Generalized

IGNITE: Study of Tirabrutinib vs Rituximab/Temozolomide for Relapsed/Refractory Primary Central Nervous System Lymphoma (PCNSL)

Phase 3 · Recruiting · Relapsed/Refractory Primary Central Nervous System Lymphoma

A Study to Evaluate the Safety, Efficacy, and PK of ONO-2017 in Japanese Patients With POS 2 to 17 Year Olds

Phase 3 · Recruiting · Partial Epilepsy

INTREPID: A Study of Sapablursen Evaluating the Safety and Efficacy in Participants With Polycythemia Vera (PV)

Phase 3 · Recruiting · Polycythemia Vera

ONO-4538 Phase II Rollover Study (ONO-4538-98)

Phase 2 · Recruiting · Pan-tumor

A Study of ONO-2020 in Patients With Agitation Associated With Alzheimer's Disease Dementia

Phase 2 · Recruiting · Agitation Associated With Alzheimer's Disease Dementia

Selected patent records

US 8188113

ripretinib · Expires 2030-07-27

US RE48731

ripretinib · Expires 2032-06-07

US 8461179

ripretinib · Expires 2034-05-15

US 10966966

ripretinib · Expires 2040-08-12

US 11266635

ripretinib · Expires 2040-08-12

US 11344536

ripretinib · Expires 2040-08-12

Primary and company sources

Company and pipeline information can change. Verify material decisions against the linked primary sources.

Evidence & limits

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