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COMPANY RESEARCH PROFILE · UPDATED 2026-09-29

Summit Therapeutics

Biopharmaceutical oncology company developing ivonescimab (SMT112), an investigational PD-1/VEGF bispecific antibody licensed from Akeso for major markets outside Akeso's retained territories.

TICKERSMMT
HEADQUARTERSFlorida, USA
STAGEPhase III
ACTIVE TRIALS5

Therapeutic areas

Oncology

Selected products and programs

ivonescimab

Linked curated drug profiles

ivonescimab

PD-1/VEGF bispecific antibody

Selected active clinical trials

Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1

Phase 3 · Recruiting · Non-Small Cell Lung Cancer

Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer

Phase 3 · Recruiting · Metastatic Colorectal Cancer (CRC)

Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients

Phase 3 · Recruiting · Non-Small Cell Lung Cancer

A Study of Ivonescimab in Combination With Enfortumab Vedotin vs Pembrolizumab in Combination With Enfortumab Vedotin in Metastatic Urothelial Carcinoma

Phase 2 · Recruiting · Metastatic Urothelial Carcinoma

Phase III Study of AK112 for NSCLC Patients

Phase 3 · Active Not Recruiting · Non-Squamous Non-small Cell Lung Cancer

Selected patent records

No linked FDA Orange Book patent record was found for the selected products.

Primary and company sources

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Evidence & limits

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/companies/summit-therapeutics/
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